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Melanotan 2, also known as MT-2, is a synthetic peptide hormone. It’s designed to mimic the effects of the naturally occurring hormone α-melanocyte-stimulating hormone (α-MSH). Just like α-MSH, it stimulates melanogenesis – the process that leads to skin darkening or tanning.
The first researchers of this peptide intended to develop a research chemical capable of promoting tanning without exposure to sunlight. Currently, this peptide is undergoing research to test its ability to enhance sexual arousal in both males and females.
The science behind this phenomenon involves receptors in the brain known as melanocortin receptors. When melanogenesis is activated by hormones such as α-MSH or substances like Melanotan 2, these receptors can affect not only skin color but also appetite and libido. The effects on the latter are currently being studied by researchers at high-end research institutions.
Melanogenesis is the body’s natural response to UV damage – it causes the body to tan as a protective mechanism against further harm.
The synthetic peptide hormone replicates the activity of alpha-melanocyte-stimulating hormone (α-MSH) to promote melanin production and release within skin cells, intensifying the natural tanning process. The α-MSH stimulates the skin cells to produce and release melanin.
α-MSH acts upon specific receptors in the body known as melanocortin receptors. Among these are MC1R, located primarily in skin cells and hair follicles, which regulate pigmentation when activated by α-MSH or Melanotan 2.
An unexpected side effect was discovered during early trials for Melanotan: participants reported an increase in sexual arousal. As scientists delved deeper into the cause of this phenomenon, they found that Melanotan also interacts with other receptors, specifically MC3R and MC4R, which are associated with sexual behavior and appetite regulation.
Future research surrounding the effects of MT2 and hypoactive sexual desire disorder must be explored.
Why wait? Discover why thousands of businesses trust the top-tier quality of our Melanotan 2. Get Yours Now!
Melanotan II is provided strictly for research purposes only. It is not approved for human consumption, medical use, cosmetic purposes, or veterinary applications.
For Research Use Only: Melanotan II is supplied exclusively for controlled laboratory testing and in vitro research.
Abuse Potential: Some individuals may attempt to misuse Melanotan II for tanning or appearance-related purposes. Such use is unsafe, unregulated, and may pose serious health risks.
Unestablished Safety: The long-term safety, pharmacology, and toxicology of Melanotan II in humans have not been determined.
Liability Disclaimer: Research Chemical assumes no liability for misuse, abuse, or handling of Melanotan II outside of legitimate research environments.
By purchasing Melanotan II, you agree it will be used solely for lawful scientific research.
1. Wessells, H., Gralnek, D., Dorr, R., Hruby, V. J., Hadley, M. E., & Levine, N. (2000). Effect of an alpha-melanocyte stimulating hormone analog on penile erection and sexual desire in men with organic erectile dysfunction. Urology, 56(4), 641-646.
2. Kublaoui, B. M., Holder Jr, J. L., Gemelli, T., & Zinn, A. R. (2006). Sim1 haploinsufficiency impairs melanocortin-mediated anorexia and activation of paraventricular nucleus neurons. Molecular Endocrinology, 20(10), 2483-2492.
3. Mubashshir, M., Ahmad, N., Sköld, H. N., & Ovais, M. (2023). An exclusive review of melatonin effects on mammalian melanocytes and melanoma. Experimental Dermatology, 32(4), 324-330.
4. Voisey, J., Carroll, L., & Van Daal, A. (2003). Melanocortins and their receptors and antagonists. Current drug targets, 4, 586-597.
5. Abdel-Malek, Z. A. (2001). Melanocortin receptors: their functions and regulation by physiological agonists and antagonists. Cellular and Molecular Life Sciences CMLS, 58, 434-441.
6. Hadley, M. E., Heward, C. B., Hruby, V. I., Sawyer, T. K., & Yang, Y. C. (1981, January). Biological actions of melanocyte‐stimulating hormone. In Ciba Foundation Symposium 81‐Peptides of the Pars Intermedia (Vol. 81, pp. 244-262). Chichester, UK: John Wiley & Sons, Ltd.
7. Rössler, A. S., Pfaus, J. G., Kia, H. K., Bernabé, J., Alexandre, L., & Giuliano, F. (2006). The melanocortin agonist, melanotan II, enhances proceptive sexual behaviors in the female rat. Pharmacology Biochemistry and Behavior, 85(3), 514-521.
8. Nasr, A., Lauterio, T. J., & Davis, M. W. (2011). Unapproved drugs in the United States and the Food and Drug Administration. Advances in therapy, 28, 842-856.
9. Caruso, C., Carniglia, L., Durand, D., Gonzalez, P. V., Scimonelli, T. N., & Lasaga, M. (2012). Melanocortin 4 receptor activation induces brain-derived neurotrophic factor expression in rat astrocytes through cyclic AMP–Protein kinase A pathway. Molecular and cellular endocrinology, 348(1), 47-54.
10. Dorr, R. T., Ertl, G., Levine, N., Brooks, C., Bangert, J. L., Powell, M. B., … & Alberts, D. S. (2004). Effects of a superpotent melanotropic peptide in combination with solar UV radiation on tanning of the skin in human volunteers. Archives of dermatology, 140(7), 827-835.
11. MacNeil, D. J., Howard, A. D., Guan, X., Fong, T. M., Nargund, R. P., Bednarek, M. A., … & Van der Ploeg, L. H. (2002). The role of melanocortins in body weight regulation: opportunities for the treatment of obesity. European journal of pharmacology, 450(1), 93-109.
Please note that the above references provide evidence for the potential benefits of Melanotan 2 Peptide as stated in the product description. For more in-depth information, kindly refer to these scholarly works.
Melanotan 2 (MT2) is a peptide that interacts with melanocortin receptors in the central nervous system, primarily targeting melanocyte stimulation. It is known for its potential to induce skin pigmentation, leading to a tanning effect, and may also have implications in appetite regulation and food intake, along with sexual behavior that are currently all under study.
Melanotan 2 has been studied for its potential impact on energy homeostasis, appetite regulation, and hunger behavior, which could have implications for body weight. However, research is ongoing, and further clinical trials are needed to establish a direct correlation between melanotan 2 and weight loss.
Yes, studies have stated that Melanotan 2 can induce skin pigmentation without sunbeds, but exposure to ultraviolet light may enhance the tanning effect.
The worst side effects reported by studies thus far of Melanotan 2 include potential adverse effects on cardiovascular health and the central nervous system, such as increased blood pressure and nausea.
Melanotan 2 is not FDA approved and is exclusively sold for research purposes. It is not intended for human consumption or use and is only available for laboratory research.
If you are searching for where to buy Melanotan online, you will come across many options. Several companies offer peptides, but unfortunately, not all prioritize quality assurance.
Research Chemical stands out in this landscape. We’re committed to delivering only the finest Melanotan 2 for sale online. When your research institution decides to buy peptides from us, rest assured, you’re opting for top-tier quality.
Our peptides undergo rigorous testing, verified by esteemed American third-party laboratories—labs that welcome phone or email inquiries to confirm their certificate’s authenticity. Our peptides for sale are preserved in lyophilized form inside glass containers and maintained in cool conditions to uphold their potency.
You can trust in our assortment of top-grade research chemicals, all backed by a reassuring 60-day money-back guarantee. Plus, enjoy free shipping for orders over $149, with expedited shipping options available. Subscribers to our newsletter enjoy a 10% discount, and choosing cryptocurrency for payment affords an additional 10% off.
Choose Research Chemical, and you’re not just selecting a seller; you’re opting for verified excellence, secured packaging, prompt deliveries, and exemplary customer service. For any queries about our Melanotan for sale or any other product, don’t hesitate to contact us. We’re here to assist promptly.
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Melanogenesis is the body’s natural response to UV damage – it causes the body to tan as a protective mechanism against further harm.
The synthetic peptide hormone replicates the activity of alpha-melanocyte-stimulating hormone (α-MSH) to promote melanin production and release within skin cells, intensifying the natural tanning process. The α-MSH stimulates the skin cells to produce and release melanin.
α-MSH acts upon specific receptors in the body known as melanocortin receptors. Among these are MC1R, located primarily in skin cells and hair follicles, which regulate pigmentation when activated by α-MSH or Melanotan 2.
An unexpected side effect was discovered during early trials for Melanotan: participants reported an increase in sexual arousal. As scientists delved deeper into the cause of this phenomenon, they found that Melanotan also interacts with other receptors, specifically MC3R and MC4R, which are associated with sexual behavior and appetite regulation.
Future research surrounding the effects of MT2 and hypoactive sexual desire disorder must be explored.
Why wait? Discover why thousands of businesses trust the top-tier quality of our Melanotan 2. Get Yours Now!
Melanotan II is provided strictly for research purposes only. It is not approved for human consumption, medical use, cosmetic purposes, or veterinary applications.
For Research Use Only: Melanotan II is supplied exclusively for controlled laboratory testing and in vitro research.
Abuse Potential: Some individuals may attempt to misuse Melanotan II for tanning or appearance-related purposes. Such use is unsafe, unregulated, and may pose serious health risks.
Unestablished Safety: The long-term safety, pharmacology, and toxicology of Melanotan II in humans have not been determined.
Liability Disclaimer: Research Chemical assumes no liability for misuse, abuse, or handling of Melanotan II outside of legitimate research environments.
By purchasing Melanotan II, you agree it will be used solely for lawful scientific research.
1. Wessells, H., Gralnek, D., Dorr, R., Hruby, V. J., Hadley, M. E., & Levine, N. (2000). Effect of an alpha-melanocyte stimulating hormone analog on penile erection and sexual desire in men with organic erectile dysfunction. Urology, 56(4), 641-646.
2. Kublaoui, B. M., Holder Jr, J. L., Gemelli, T., & Zinn, A. R. (2006). Sim1 haploinsufficiency impairs melanocortin-mediated anorexia and activation of paraventricular nucleus neurons. Molecular Endocrinology, 20(10), 2483-2492.
3. Mubashshir, M., Ahmad, N., Sköld, H. N., & Ovais, M. (2023). An exclusive review of melatonin effects on mammalian melanocytes and melanoma. Experimental Dermatology, 32(4), 324-330.
4. Voisey, J., Carroll, L., & Van Daal, A. (2003). Melanocortins and their receptors and antagonists. Current drug targets, 4, 586-597.
5. Abdel-Malek, Z. A. (2001). Melanocortin receptors: their functions and regulation by physiological agonists and antagonists. Cellular and Molecular Life Sciences CMLS, 58, 434-441.
6. Hadley, M. E., Heward, C. B., Hruby, V. I., Sawyer, T. K., & Yang, Y. C. (1981, January). Biological actions of melanocyte‐stimulating hormone. In Ciba Foundation Symposium 81‐Peptides of the Pars Intermedia (Vol. 81, pp. 244-262). Chichester, UK: John Wiley & Sons, Ltd.
7. Rössler, A. S., Pfaus, J. G., Kia, H. K., Bernabé, J., Alexandre, L., & Giuliano, F. (2006). The melanocortin agonist, melanotan II, enhances proceptive sexual behaviors in the female rat. Pharmacology Biochemistry and Behavior, 85(3), 514-521.
8. Nasr, A., Lauterio, T. J., & Davis, M. W. (2011). Unapproved drugs in the United States and the Food and Drug Administration. Advances in therapy, 28, 842-856.
9. Caruso, C., Carniglia, L., Durand, D., Gonzalez, P. V., Scimonelli, T. N., & Lasaga, M. (2012). Melanocortin 4 receptor activation induces brain-derived neurotrophic factor expression in rat astrocytes through cyclic AMP–Protein kinase A pathway. Molecular and cellular endocrinology, 348(1), 47-54.
10. Dorr, R. T., Ertl, G., Levine, N., Brooks, C., Bangert, J. L., Powell, M. B., … & Alberts, D. S. (2004). Effects of a superpotent melanotropic peptide in combination with solar UV radiation on tanning of the skin in human volunteers. Archives of dermatology, 140(7), 827-835.
11. MacNeil, D. J., Howard, A. D., Guan, X., Fong, T. M., Nargund, R. P., Bednarek, M. A., … & Van der Ploeg, L. H. (2002). The role of melanocortins in body weight regulation: opportunities for the treatment of obesity. European journal of pharmacology, 450(1), 93-109.
Please note that the above references provide evidence for the potential benefits of Melanotan 2 Peptide as stated in the product description. For more in-depth information, kindly refer to these scholarly works.
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