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Research Chemical products are third-party tested by MZ Biolabs, an independent laboratory based in Arizona. Each batch is analyzed to ensure accuracy, purity, and that all specifications are met.
RAD-140 (Testolone) is a selective androgen receptor modulator (SARM)—part of the broader class of selective androgen receptor modulators—originally developed as a potential treatment for muscle wasting conditions and osteoporosis. It works by selectively binding to androgen receptors in muscle and bone tissues with high affinity, which may lead to anabolic effects, including increases in lean muscle mass and potential support for bone health. RAD-140 is also orally bioavailable, distinguishing it from some androgenic agents that require injection.
Preclinical research has examined RAD-140 for its androgen receptor selectivity and tissue-targeted anabolic activity, setting it apart mechanistically and in early safety data from traditional anabolic androgenic steroids. Early studies have explored its potential roles in muscle atrophy, osteoporosis, and hormone receptor–positive breast cancers. However, RAD-140 remains an investigational compound and is not approved for use in humans.
Research, including work by Deuster and Silverman (2013), has discussed the pharmacology, potential applications, and risks associated with SARMs such as RAD-140 in both medical and research contexts.
Importantly, while RAD-140 is legally available for laboratory research purposes, claims that it is “10× more anabolic than testosterone” or categorically superior are not supported by peer-reviewed human data. Current evidence is largely preclinical or derived from early-phase clinical oncology studies.
RAD-140 (Testolone) binds to androgen receptors with high selectivity, preferentially activating anabolic pathways in muscle and bone tissues. This receptor selectivity is a primary focus of ongoing research, as it may allow anabolic effects while minimizing androgenic activity compared to traditional anabolic steroids.
Preclinical studies have shown that RAD-140 has minimal impact on the prostate relative to non-selective steroids. In animal models, no significant increase in prostate weight was observed, supporting its tissue-selective activity (Miller et al., 2011).
Preclinical and early clinical investigations have examined RAD-140 for its:
Additionally, RAD-140 has been studied for potential anti-proliferative effects in certain hormone receptor–positive breast cancer models, indicating possible applications in oncology research (Yu et al., 2017; LoRusso et al., 2022).
Important Notice: All applications listed above are restricted to laboratory research use only. RAD-140 is not FDA-approved, not classified as a dietary supplement, and is prohibited by the World Anti-Doping Agency (WADA). Misuse of this compound may pose significant health risks.
CAS Number: 1182367-47-0
Chemical Formula: C₂₀H₁₆ClN₅O₂
Molar Mass: 393.83 g/mol
Half-Life: Approx. 44.7 hours
Classification: Selective Androgen Receptor Modulator (SARM)
Each batch of RAD-140 is verified through third-party analysis to ensure purity and chemical accuracy. RAD-140 is not approved for human consumption, and its use is restricted to laboratory research purposes only.
Volume: 30ml per bottle
Concentration: 15mg/mL
Purity: ≥98% (verified by third-party analysis)
Chemical Composition: The chemical composition of each batch is confirmed through third-party analysis to ensure quality and safety.
Measurement Tool: Includes a graduated 1mL glass pipette for precise calculations
Packaging: UV-resistant glass bottle with a tamper-proof seal
Storage Instructions: Store in a cool, dry place away from open air exposure and sunlight to prevent degradation
Stability: Specially packaged to prevent evaporation; <5% variance in concentration for consistent research results
The FDA and WADA have issued warnings regarding SARMs due to potential safety risks and illicit marketing as dietary supplements. RAD-140, like all SARMs, is prohibited under WADA regulations.
Research Chemical provides high-purity Liquid RAD-140 for scientific investigation only. RAD-140 has been studied in preclinical models for its androgen receptor selectivity and tissue-targeted anabolic activity, as well as in early oncology trials. Some preclinical research suggests that RAD-140 may influence bone density and skeletal strength, making it of interest in studies related to conditions such as osteoporosis, though human clinical evidence remains limited.
RAD-140 is not approved for medical or dietary use, and its misuse outside controlled research environments carries significant health risks. Documented and potential adverse effects include:
Unlike anabolic steroids, SARMs typically do not aromatize to estrogen, but their safety profiles are still under investigation. RAD-140 has been associated with drug-induced liver injury, often showing a cholestatic pattern. A documented case involving a 24-year-old male demonstrated significant elevations in liver enzymes, which resolved after discontinuation (Mertens et al., 2024; Jayaraman et al., 2014).
This highlights the importance of restricting RAD-140 to controlled research use with appropriate safety monitoring. RAD-140 should be used strictly within legitimate laboratory research settings. It is not approved for bodybuilding, performance enhancement, or any human use. RAD-140 is also prohibited by the World Anti-Doping Agency (WADA).
RAD-140 is not an aromatase inhibitor, although it is being explored in hormone-sensitive cancer research contexts that sometimes overlap with therapeutic areas where aromatase inhibitors are used. Its role in these pathways remains investigational and is not interchangeable with approved hormone therapies.
The safety of RAD-140, a selective androgen receptor modulator (SARM), is a critical factor for any research or experimental protocol. Clinical trials and preclinical studies have demonstrated that RAD-140 can promote muscle growth and increase lean body mass, as well as support bone density. However, these potential benefits must be weighed against the risks associated with its use. Notably, RAD-140 has been linked to drug-induced liver injury, with documented cases of liver enzyme elevations and cholestatic liver injury. Additionally, RAD-140 can suppress natural testosterone production, leading to possible side effects such as fatigue, decreased libido, and, in some cases, hair loss.
With the growing interest in SARMs like RAD-140, ensuring product quality and authenticity has become more important than ever. The market is unfortunately rife with substances marketed as SARMs that may not contain the correct chemical composition, or may be adulterated with other, potentially harmful compounds. To safeguard both efficacy and safety, it is essential to source RAD-140 exclusively from reputable vendors who provide comprehensive third-party lab testing and verification.
Reliable suppliers, like Research Chemical, will offer certificates of analysis confirming the identity and purity of RAD-140, minimizing the risk of exposure to unknown substances. This level of quality control is crucial for research integrity and for reducing the risk of adverse effects associated with impure or mislabeled products. By prioritizing authentication and transparency, researchers can ensure that their studies are based on genuine RAD-140, thereby supporting accurate results and maintaining high safety standards.
The subjective nature of testimonials means that individual experiences can vary widely, and some reviews may be influenced by bias or lack of scientific rigor. Furthermore, the risks associated with RAD 140—such as potential liver toxicity and hormonal imbalances—should not be underestimated. When evaluating clinical feedback, it is essential to consider the broader context of clinical and preclinical research, and to recognize that safety and efficacy can only be reliably assessed through controlled scientific studies.
The regulatory landscape for RAD-140 is complex and varies significantly across jurisdictions. In the United States, RAD-140 is not approved by the FDA for human consumption and is classified as a research chemical. Despite this, it is sometimes found in products marketed as dietary supplements or performance enhancers, which can create confusion and potential legal risks.
For those involved in research or considering the use of RAD-140, it is vital to understand and comply with all relevant laws and regulations. The use of RAD-140 for bodybuilding or performance enhancement is not sanctioned by regulatory authorities and violates anti-doping rules in competitive sports. Ensuring that RAD-140 is used strictly for legitimate research purposes and only sourced from compliant vendors is essential for maintaining both legal and ethical standards.
This RAD-140 formulation is supplied strictly for laboratory research use only. The FDA has not approved SARMs for human use, and long-term effects remain unknown. RAD-140 is prohibited by WADA in all athletic competitions.
Misuse of RAD-140 outside sanctioned research may pose significant health risks, including liver stress, hormonal disruption, and other adverse effects. This product is not intended for human or animal consumption, treatment, diagnosis, or prevention of disease.
The information provided is for educational purposes only and does not constitute medical advice.
Yes, RAD-140 is legal to purchase and possess for laboratory research use only. It is not approved for human consumption.
RAD-140 is among the substances marketed for research use only and is not intended for human consumption. No prescription is required to purchase RAD 140 as a research chemical.
No. RAD-140 (Testolone) is not a dietary supplement and must never be used outside of controlled scientific environments.
RAD 140 is not approved for use in food or dietary supplements, and its chemical composition is strictly regulated for research purposes only.
Store in a cool, dry place, tightly sealed and away from direct light or humidity to ensure maximum shelf life and chemical stability.
Research Chemical offers pharmaceutical-grade Liquid RAD 140 designed exclusively for laboratory research use. Known as Testolone, RAD 140 is a Selective Androgen Receptor Modulator (SARM) extensively studied for its potential influence on muscle growth, lean muscle mass, and bone health.
This compound interacts with androgen receptors with high affinity and selectivity, making it a powerful tool in studies related to body composition, strength gains, and anabolic pathways.
The future development of RAD 140 is centered on ongoing scientific investigation into its potential applications in several medical research areas. Preclinical and early clinical studies are exploring RAD 140’s role in addressing muscle wasting conditions, including sarcopenia and cancer cachexia, as well as its potential to influence bone density and reduce fracture risk. In addition, RAD 140 is being studied as a possible therapeutic candidate for certain androgen receptor–positive breast cancers, particularly in early-phase oncology trials.
As the field of selective androgen receptor modulators (SARMs) continues to evolve, further research will be critical to fully understanding their mechanisms of action, safety profiles, and potential clinical applications. Additional controlled clinical trials and long-term studies will be necessary to assess both benefits and risks, including hormonal and hepatic safety considerations.
By supporting rigorous, peer-reviewed scientific inquiry, researchers can better evaluate RAD 140’s role in muscle, bone, and hormone-related pathways and determine whether it may contribute to future therapeutic strategies. At present, RAD 140 remains an investigational compound and is not approved for medical use.
Browse our selection of high-quality SARMs and peptides, and experience why Research Chemical is the best place to buy RAD 140 and other research-grade compounds.
Looking for alternatives? Explore our Ligandrol LGD-4033 or YK-11 research chemicals—these are other SARMs available for research purposes.
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RAD-140 (Testolone) binds to androgen receptors with high selectivity, preferentially activating anabolic pathways in muscle and bone tissues. This receptor selectivity is a primary focus of ongoing research, as it may allow anabolic effects while minimizing androgenic activity compared to traditional anabolic steroids.
Preclinical studies have shown that RAD-140 has minimal impact on the prostate relative to non-selective steroids. In animal models, no significant increase in prostate weight was observed, supporting its tissue-selective activity (Miller et al., 2011).
Preclinical and early clinical investigations have examined RAD-140 for its:
Additionally, RAD-140 has been studied for potential anti-proliferative effects in certain hormone receptor–positive breast cancer models, indicating possible applications in oncology research (Yu et al., 2017; LoRusso et al., 2022).
CAS Number: 1182367-47-0
Chemical Formula: C₂₀H₁₆ClN₅O₂
Molar Mass: 393.83 g/mol
Half-Life: Approx. 44.7 hours
Classification: Selective Androgen Receptor Modulator (SARM)
Each batch of RAD-140 is verified through third-party analysis to ensure purity and chemical accuracy. RAD-140 is not approved for human consumption, and its use is restricted to laboratory research purposes only.
Volume: 30ml per bottle
Concentration: 15mg/mL
Purity: ≥98% (verified by third-party analysis)
Chemical Composition: The chemical composition of each batch is confirmed through third-party analysis to ensure quality and safety.
Measurement Tool: Includes a graduated 1mL glass pipette for precise calculations
Packaging: UV-resistant glass bottle with a tamper-proof seal
Storage Instructions: Store in a cool, dry place away from open air exposure and sunlight to prevent degradation
Stability: Specially packaged to prevent evaporation; <5% variance in concentration for consistent research results
The FDA and WADA have issued warnings regarding SARMs due to potential safety risks and illicit marketing as dietary supplements. RAD-140, like all SARMs, is prohibited under WADA regulations.
Research Chemical provides high-purity Liquid RAD-140 for scientific investigation only. RAD-140 has been studied in preclinical models for its androgen receptor selectivity and tissue-targeted anabolic activity, as well as in early oncology trials. Some preclinical research suggests that RAD-140 may influence bone density and skeletal strength, making it of interest in studies related to conditions such as osteoporosis, though human clinical evidence remains limited.
RAD-140 is not approved for medical or dietary use, and its misuse outside controlled research environments carries significant health risks. Documented and potential adverse effects include:
Unlike anabolic steroids, SARMs typically do not aromatize to estrogen, but their safety profiles are still under investigation. RAD-140 has been associated with drug-induced liver injury, often showing a cholestatic pattern. A documented case involving a 24-year-old male demonstrated significant elevations in liver enzymes, which resolved after discontinuation (Mertens et al., 2024; Jayaraman et al., 2014).
This highlights the importance of restricting RAD-140 to controlled research use with appropriate safety monitoring. RAD-140 should be used strictly within legitimate laboratory research settings. It is not approved for bodybuilding, performance enhancement, or any human use. RAD-140 is also prohibited by the World Anti-Doping Agency (WADA).
RAD-140 is not an aromatase inhibitor, although it is being explored in hormone-sensitive cancer research contexts that sometimes overlap with therapeutic areas where aromatase inhibitors are used. Its role in these pathways remains investigational and is not interchangeable with approved hormone therapies.
The safety of RAD-140, a selective androgen receptor modulator (SARM), is a critical factor for any research or experimental protocol. Clinical trials and preclinical studies have demonstrated that RAD-140 can promote muscle growth and increase lean body mass, as well as support bone density. However, these potential benefits must be weighed against the risks associated with its use. Notably, RAD-140 has been linked to drug-induced liver injury, with documented cases of liver enzyme elevations and cholestatic liver injury. Additionally, RAD-140 can suppress natural testosterone production, leading to possible side effects such as fatigue, decreased libido, and, in some cases, hair loss.
With the growing interest in SARMs like RAD-140, ensuring product quality and authenticity has become more important than ever. The market is unfortunately rife with substances marketed as SARMs that may not contain the correct chemical composition, or may be adulterated with other, potentially harmful compounds. To safeguard both efficacy and safety, it is essential to source RAD-140 exclusively from reputable vendors who provide comprehensive third-party lab testing and verification.
Reliable suppliers, like Research Chemical, will offer certificates of analysis confirming the identity and purity of RAD-140, minimizing the risk of exposure to unknown substances. This level of quality control is crucial for research integrity and for reducing the risk of adverse effects associated with impure or mislabeled products. By prioritizing authentication and transparency, researchers can ensure that their studies are based on genuine RAD-140, thereby supporting accurate results and maintaining high safety standards.
The subjective nature of testimonials means that individual experiences can vary widely, and some reviews may be influenced by bias or lack of scientific rigor. Furthermore, the risks associated with RAD 140—such as potential liver toxicity and hormonal imbalances—should not be underestimated. When evaluating clinical feedback, it is essential to consider the broader context of clinical and preclinical research, and to recognize that safety and efficacy can only be reliably assessed through controlled scientific studies.
The regulatory landscape for RAD-140 is complex and varies significantly across jurisdictions. In the United States, RAD-140 is not approved by the FDA for human consumption and is classified as a research chemical. Despite this, it is sometimes found in products marketed as dietary supplements or performance enhancers, which can create confusion and potential legal risks.
For those involved in research or considering the use of RAD-140, it is vital to understand and comply with all relevant laws and regulations. The use of RAD-140 for bodybuilding or performance enhancement is not sanctioned by regulatory authorities and violates anti-doping rules in competitive sports. Ensuring that RAD-140 is used strictly for legitimate research purposes and only sourced from compliant vendors is essential for maintaining both legal and ethical standards.
This RAD-140 formulation is supplied strictly for laboratory research use only. The FDA has not approved SARMs for human use, and long-term effects remain unknown. RAD-140 is prohibited by WADA in all athletic competitions.
Misuse of RAD-140 outside sanctioned research may pose significant health risks, including liver stress, hormonal disruption, and other adverse effects. This product is not intended for human or animal consumption, treatment, diagnosis, or prevention of disease.
The information provided is for educational purposes only and does not constitute medical advice.
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