Description
Buy RU-58841 for Research
RU-58841 is a topical non-steroidal anti-androgen that has garnered significant attention in experimental dermatological research. Initially investigated for its ability to block dihydrotestosterone (DHT) at the receptor level, RU58841 is a potent androgen receptor antagonist used in models studying androgenic alopecia and related hair follicle responses.
RU-58841 Mechanism of Action
RU-58841 selectively binds to androgen receptors in the skin, blocking the interaction with DHT, the androgen strongly associated with male pattern baldness and sebaceous gland activity. It does not significantly impact systemic testosterone levels or hormonal profiles in topical applications under controlled experimental settings.
Scientific Research Applications
RU-58841 has been explored in laboratory models for its potential to:
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Inhibit DHT binding at androgen receptors in the skin
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Support studies related to androgenic alopecia and scalp follicle sensitivity
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Investigate localized anti-androgenic effects without systemic impact
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Examine the androgen-mediated gene expression in dermal papilla cells
While RU58841 is not FDA-approved for medical or cosmetic use, its receptor-specific action has made it a compound of interest in androgen-related dermatological research.
FAQs for Liquid RU-58841
Can RU58841 be used as a supplement?
No. It is not a dietary or sports supplement and is not for human use.
Is RU58841 FDA approved?
No. RU58841 is not approved by the FDA and is intended strictly for research purposes.
How do I accurately measure RU58841?
Each dropper has measurements up to the 1ml line.
What is the concentration of this solution?
Each 30mL bottle contains RU58841 at a concentration of 50mg/mL.
What is RU58841?
RU58841 is a non-steroidal topical anti-androgen developed for research and is being studied for its effects on hair loss and androgen-mediated skin conditions.
Product Overview
Compound Name: RU-58841
CAS Number: 154992-24-2
Chemical Formula: C₁₇H₁₈F₃N₃O₃
Molar Mass: 369.3 g/mol
Classification: Non-Steroidal Androgen Receptor Antagonist
Key Product Specifications
High Concentration: 50mg/mL solution in a 30mL bottle
Packaging: UV-protected amber glass bottle with tamper-proof seal
Purity: ≥99% purity, with <5% batch variance
Storage: Store in a cool, dry place away from direct sunlight
Use: Intended strictly for laboratory research purposes
Why Choose Us for Your Research Needs?
Verified Purity: Third-party batch testing for quality assurance
Secure Packaging: UV-protected, leak-proof, and tamper-resistant bottles
Reliable Fulfillment: Fast, discreet shipping with tracked delivery
Supportive Team: Expert assistance for research-based questions
Scientific References
1. Frizza, F., Maggi, M., & Lotti, F. (2023). Skin Androgen-Related Disorders: Hormonal Treatment. In European Handbook of Dermatological Treatments (pp. 1661-1678). Cham: Springer International Publishing.
2. Münster, U., NakamuraNachname, C., Haberland, A., Jores, K., Mehnert, W., Rummel, S., … & Schäfer-Korting, M. (2005). RU 58841-myristate–prodrug development for topical treatment of acne and androgenetic alopecia. Die Pharmazie-An International Journal of Pharmaceutical Sciences, 60(1), 8-12.
3. De Brouwer, B., Tetelin, C., Leroy, T., Bonfils, A., & Van Neste, D. (1997). A controlled study of the effects of RU58841, a non‐steroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosterone‐conditioned nude mice. British Journal of Dermatology, 137(5), 699-702.
4. Pan, H. J., Wilding, G., Uno, H., Inui, S., Goldsmith, L., Messing, E., & Chang, C. (1998). Evaluation of RU58841 as an anti-androgen in prostate PC3 cells and a topical anti-alopecia agent in the bald scalp of stumptailed macaques. Endocrine, 9, 39-43.
